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Tech Alley http://techalley.cirne.com Covering Technology in the San Francisco Bay Area Tue, 14 Oct 2014 08:28:15 +0000 en-US hourly 1 http://wordpress.org/?v=4.0.18 Before We Can Add Years to Life, We Must Add Life to Years http://techalley.cirne.com/2008/09/14/before-we-can-add-years-to-life-we-must-add-life-to-years/ http://techalley.cirne.com/2008/09/14/before-we-can-add-years-to-life-we-must-add-life-to-years/#comments Mon, 15 Sep 2008 00:44:59 +0000 http://techalley.cirne.com/2008/09/14/before-we-can-add-years-to-life-we-must-add-life-to-years/ Before We Can Add Years to Life, We Must Add Life to Years
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On June 28th Dr. Laura Briggs of Sierra Sciences talked at the Aging 2008 Conference in UCLA on "The Struggle to Keep our Telomeres Long."

The talk is 33 minutes long and described as:

One basic quality of human life is that every time our cells divide the tips of our chromosomes get shorter. This shortening of telomeres may be the molecular clock of aging. Indeed, the shortening of telomeres has been shown to be the trigger that induces senescence of human cells grown in culture; whether this can be extrapolated to include human organismal aging itself is not yet known. The correlation between telomere length and age is very strong and shorter telomeres directly correspond to shorter human life expectancy, but "cause and effect" are still debated. Finding ways to prevent telomere shortening could be an ideal way to address these issues and answer the question once and for all: Does prevention of telomere shortening extend our lifespans? It is unfortunate that anything that is done to extend the lifespan of our cells will also extend the lifespan of our cancer cells. Excision of the telomerase gene and genes involved in the "Alternative Lengthening of Telomeres" (ALT) pathway is one way to overcome this cancer issue. But our lifespan will be limited more than ever by the length of our telomeres. This leaves us with the irrefutable conclusion that we will be unable to significantly extend our lifespans without finding a cure for cancer that doesn't limit our ability to extend the lengths of our telomeres. In hopes that the cure for cancer will be forthcoming, several biotech organizations and academic institutions have accepted the challenge of finding ways to prevent telomere shortening by transiently inducing the activity of telomerase. The purpose of this presentation will be to review the current progress, including the recent discovery of several small molecules that induce telomerase activity in normal human cells.

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Aging 2008 panel Q&A: How Fast Will Stem Cell Research Adavance http://techalley.cirne.com/2008/07/09/aging-2008-panel-qa-how-fast-will-stem-cell-research-adavance/ http://techalley.cirne.com/2008/07/09/aging-2008-panel-qa-how-fast-will-stem-cell-research-adavance/#comments Wed, 09 Jul 2008 19:58:45 +0000 http://techalley.cirne.com/2008/07/09/aging-2008-panel-qa-how-fast-will-stem-cell-research-adavance/ Aging 2008 panel Q&A: How Fast Will Stem Cell Research Adavance
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During the panel at Aging 2008, Michael West, Gregory Stock and William Haseltine respond to how quickly stem cell research is expected to produce results.

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Michael West announces Embryome.com http://techalley.cirne.com/2008/07/07/michael-west-announces-embryomecom/ http://techalley.cirne.com/2008/07/07/michael-west-announces-embryomecom/#comments Tue, 08 Jul 2008 04:34:53 +0000 http://techalley.cirne.com/2008/07/07/michael-west-announces-embryomecom/ Michael West announces Embryome.com
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During the panel discussion at Aging 2008, Michael West announced embroyone.com. A wikipedia or database for stem cell research.]]>
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Leading up to Aging 2008 http://techalley.cirne.com/2008/07/05/leading-up-to-aging-2008/ http://techalley.cirne.com/2008/07/05/leading-up-to-aging-2008/#comments Sun, 06 Jul 2008 01:42:26 +0000 http://techalley.cirne.com/2008/07/05/leading-up-to-aging-2008/ Leading up to Aging 2008
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I went to Los Angeles on Friday, June 28th for the Aging 2008 (and Understand Aging) conference. This is a look around UCLA Royce Hall before the conference.]]>
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Back from Understanding Aging conference http://techalley.cirne.com/2008/06/30/back-from-understanding-aging-conference/ http://techalley.cirne.com/2008/06/30/back-from-understanding-aging-conference/#comments Mon, 30 Jun 2008 22:28:09 +0000 http://techalley.cirne.com/2008/06/30/back-from-understanding-aging-conference/ Just got back from the Understanding Aging conference. I'll soon have some video up here. And will announce a new on near future predictions where more of this type of material will exist.]]> http://techalley.cirne.com/2008/06/30/back-from-understanding-aging-conference/feed/ 0 Ars Technica & Gizmodo WWDC Party http://techalley.cirne.com/2008/06/15/ars-technica-gizmodo-wwdc-party/ http://techalley.cirne.com/2008/06/15/ars-technica-gizmodo-wwdc-party/#comments Sun, 15 Jun 2008 23:43:05 +0000 http://techalley.cirne.com/2008/06/15/ars-technica-gizmodo-wwdc-party/ Ars Technica & Gizmodo WWDC Party
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The Ars Technica & Gizmodo WWDC Party on June 10th at Harlot.]]>
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Richard Stallman’s Ethics http://techalley.cirne.com/2007/09/13/richard-stallmans-ethics/ http://techalley.cirne.com/2007/09/13/richard-stallmans-ethics/#comments Thu, 13 Sep 2007 17:06:12 +0000 http://techalley.cirne.com/2007/09/13/richard-stallmans-ethics/

Photo from chrys photostream

I went to listen to Richard Stallman at U.C. Berkeley on "Copyright vs Community in the Age of Computer Networks". At the end I asked Richard about my publishing software under LGPL with one part free (PHP and javascript code) and another part copyrighted (flash code.) He told me I was unethical. From his talk and writing, I gather the ethics are that I'm not allowing someone else the ability to see and modify the code I've written in the Flash portion.

I respect Richard's personal ethic to share all code that he's written. I disagree with him imposing his personal ethics and methods on others.

Not everyone else has the same needs and requirements with software and other products as Richard. Many do not want to and will not modify computer code. More essential, an exchange of work performed is a contract between two or more individuals. It's a negotiation where both parties find the best agreement for a product. In the future some or all of the Flash source code may be available. And it is likely available on a negotiated basis. But to require only one method of disseminating coded takes away the freedom to distributing and negotiating work. That is unethical.

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iPhoneDevCamp Walkthrough http://techalley.cirne.com/2007/07/07/iphonedevcamp-walkthrough/ http://techalley.cirne.com/2007/07/07/iphonedevcamp-walkthrough/#comments Sun, 08 Jul 2007 03:17:01 +0000 http://techalley.cirne.com/2007/07/07/iphonedevcamp-walkthrough/ iPhoneDevCamp Walkthrough
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I arrived at iPhoneDevCamp Saturday, June 7th, mid-afternoon. I walked through shooting people intently working on their hacks.

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JPG Magazine Party http://techalley.cirne.com/2007/04/30/jpg-magazine-party/ http://techalley.cirne.com/2007/04/30/jpg-magazine-party/#comments Mon, 30 Apr 2007 21:45:58 +0000 http://techalley.cirne.com/2007/04/30/jpg-magazine-party/ JPG Magazine Party
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On April 20th JPG Magazine threw a party at SFAC Gallery.

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SupperHappyDevHouse 0b10000 http://techalley.cirne.com/2007/03/25/supperhappydevhouse-0b10000/ http://techalley.cirne.com/2007/03/25/supperhappydevhouse-0b10000/#comments Mon, 26 Mar 2007 01:36:34 +0000 http://techalley.cirne.com/2007/03/25/supperhappydevhouse-0b10000/

Video of SupperHappyDevHouse 16 shot for 10 seconds every 30 minutes.

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